Birefringent property of hypercholesterolemic rabbit serum.

CHOLESTEROL LOWERING EFFECT OF RHEUM RIBS IN HYPERCHOLESTEROLEMIC RABBITS

The effects of ethanolic and aqueous extracts of Rheum ribs L. (RR) of the family polygonaceae was studied on serum cholesterol concentration in rabbits. To induce hypercholesterolemia, 0.5 g/kg/day of pure cholesterol powder was given orally to each rabbit for two weeks then cholesterol was halved and each group of animals was treated with a different regimen for another two weeks. Both t...

Differential alteration of vascular reactivity in rabbit aorta with modest elevation of serum cholesterol.

The effect of diet-induced, moderate elevation of serum cholesterol on vascular reactivity in isolated rabbit abdominal aortic rings was examined by using a series of vasoconstrictor and vasodilator agonists. Serum cholesterol of rabbits that were fed a cholesterol-free, casein-rich diet for 10 weeks was elevated approximately 4.5-fold compared with values found in control rabbits that were fed...

Antihyperlipidemic Effects of Sesamum indicum L. in Rabbits Fed a High-Fat Diet

The present study aimed to investigate the anti-hyperlipidemic effects of sesame in a high-fat fed rabbit model. Animals were randomly divided into four groups of eight animals each for 60 days as follows: normal diet, hypercholesterolemic diet (1% cholesterol), hypercholesterolemic diet (1% cholesterol) + sesame seed (10%), and hypercholesterolemic diet (1% cholesterol) + sesame oil (5%). Seru...

Cholesterol synthesis and esterification in experimental xanthoma tissues.

We studied cholesterol metabolism in experimental xanthoma tissues which were induced by injection of high molecular weight sodium dextran sulfate into the dermis of hypercholesterolemic rabbits. Control studies were performed on dermal specimens of the dextran sulfate-injected site of normolipemic rabbits. Cholesterol accumulation was much greater in the hypercholesterolemic rabbit tissues tha...

Reduction of serum cholesterol in hypercholesterolemic rats by Guar gum